2026
Arnold N, Riccio C, Blankenberg S, Ziegler A & Twerenbold R 2026 In reply. Dtsch Arztebl Int, 123–m1061. doi: 10.3238/arztebl.m2026.0013
Bleiziffer S, Leuschner F, Rudolph TK, Vonthein R, et al. 2026 Sex-specific outcomes after transcatheter or surgical treatment of aortic valve stenosis: the DEDICATE-DZHK6 trial. Eur Heart J, 47:1339–1353. doi: 10.1093/eurheartj/ehaf519
Di Carluccio E, Ogutu S, Köse O, Mwambi HG, Ziegler A, Confidence Intervals for Comparing Two Independent Folded Normals: A Case Study in Bunion Surgery. Stat Med. 2026 Mar; doi: 10.1002/sim.70494
Riedl KA, Di Carluccio E, Huellebrand M, et al. 2026 Associations between cardiovascular risk factors and diseases with aortic pulse wave velocity and aortic distensibility: magnetic resonance imaging in the Hamburg City Health Study. Clin Res Cardiol, 115:1389–1399. doi: 10.1007/s00392-026-02866-x
Schrage B, Lackner MK, Hoshiyar A, et al. 2026 Emulated effects of glucagon-like peptide 1 receptor agonist therapy in the general population. J Am Coll Cardiol, 87:2948–2959. doi: 10.1016/j.jacc.2026.01.055
2025
Betschart RO, Thalén F, Blankenberg S, Zoche M, Zeller T & Ziegler A 2025 A benchmark study of compression software for human short-read sequence data. Sci Rep, 15:15358. doi: 10.1038/s41598-025-00491-8
The Global Cardiovascular Risk Consortium 2025 Global effect of cardiovascular risk factors on lifetime estimates. N Engl J Med, 393:125-38; doi: 10.1056/NEJMoa2415879
Ludwig S, Klimek M, Bay B, Blankenberg S, et al. 2025 Transcatheter or surgical treatment of patients with aortic stenosis at low to intermediate Riskr: an individual participant data meta-analysis. JAMA Cardiol, in press. doi: 10.1001/jamacardio.2025.3403.
Riccio C, Arnold N, Koliopanos G, et al. 2025 Familial hypercholesterolemia: prevalence and discrepancy between genotype and phenotype. Findings of the population-based Hamburg City Health Study. Dtsch Arztebl Int, 122:511–6. doi: 10.3238/arztebl.m2025.0110.
Riccio C, Jansen ML, Thalén F, et al. 2025 Assessment of the functionality and usability of open-source rare variant analysis pipelines, Brief Bioinf 26:bbaf044 doi: 10.1093/bib/bbaf044
Riedl KA, Koliopanos G, Albrecht JN, et al. 2025 Assessment of aortic and mitral valve regurgitation volumes by cardiovascular magnetic resonance in participants without valvular heart disease in the Hamburg City Health Study population. Int J Cardiovasc Imaging, 41:2343–2352. doi: 10.1007/s10554-025-03538-z
Ziegler A & Schmid M 2025 Efficient study designs for the early-stage evaluation of disease-modifying treatments in Parkinson disease, Neurology 104:e210218 doi: 10.1212/WNL.0000000000210218
2024
Betschart RO, Koliopanos G, Garg P, et al. 2024 Comprehensive analysis of the genetic variation in the LPA gene from short-read sequencing. BioMed 4:156-70; doi: 10.3390/biomed4020013
Betschart RO, Riccio C, Aguilera-Garcia D, et al. 2024 Biostatistical aspects of whole genome sequencing studies: pre-processing and quality control. Biom J 66:e202300278; doi: 10.1002/bimj.202300278
Blankenberg S, Seiffert M, Vonthein R, et al. 2024 Transcatheter or surgical treatment of aortic-valve stenosis. N Engl J Med 390:1572-83; doi: 10.1056/NEJMoa2400685
Cavus E, Schneider JN, di Carluccio E, et al. 2024 Unrecognized myocardial scar by Late-Gadolinium-Enhancement cardiovascular magnetic resonance: insights from the population-based Hamburg City Health Study. J Cardiovasc Magn Reson 26:101008; doi: 10.1016/j.jocmr.2024.101008
Grau I & Ziegler A 2024 Wie gestaltet man einen Fragebogen? Praktische Tipps zur Formulierung der Fragen und der Konstruktion des Fragebogens [How to design a questionnaire? Practical tips on formulating the questions and constructing the questionnaire]. Dtsch Med Wochenschr 149:113-27; doi: 10.1055/a-2186-1587
Ojeda FM, Baker SG & Ziegler A 2024 Calibrating machine learning approaches for probability estimation: a short expansion. Stat Med 43:4212-5; doi:10.1002/sim.10051
Riccio C, Jansen ML, Guo L & Ziegler A 2024 Variant effect predictors: a systematic review and practical guide. Hum Genet 143:625-34; doi: 10.1007/s00439-024-02670-5
Speiser JL, Kerr WT & Ziegler A 2024 Common critiques and recommendations for studies in Neurology using machine learning methods. Neurology 103:e209861; doi:10.1212/WNL.0000000000209861
Toprak B, Solleder H, di Carluccio E, et al. 2024 Diagnostic accuracy of a machine learning algorithm using point-of-care high-sensitivity cardiac troponin I for rapid rule-out of myocardial infarction: a retrospective study. Lancet Digit Health 6:e729-8; doi:10.1016/S2589-7500(24)00191-2
Ziegler A, Eliasziw M, Howard VJ, et al. 2024. New requirements in the reporting of randomized controlled trials published in Neurology to foster greater transparency. Neurology 103:e209909; doi:10.1212/WNL.0000000000209909
2023
Heßler N & Ziegler A 2023 Content and form of original research articles in general major medical journals. PLoS One 18:e0287677; doi: 10.1371/journal.pone.0287677
Koliopanos G, Ojeda F & Ziegler A 2023 A simple-to-use R package for mimicking study data by simulations. Methods Inf Med 62:119-29; doi: 10.1055/a-2048-7692
Magnussen C, Ojeda FM, Leong DP, et al. 2023 Global effect of modifiable risk factors on cardiovascular disease and mortality. N Engl J Med 389:1273-85; doi: 10.1056/NEJMoa220691
Neumann JT, Twerenbold R, Orjeda F, et al. 2023 Personalized diagnosis in suspected myocardial infarction. Clin Res Cardiol 112:1288-1301; doi: 10.1007/s00392-023-02206-3
Ojeda F, Jansen ML, Thiéry A, et al. 2023 Calibrating machine learning approaches for probability estimation: a comprehensive comparison. Stat Med 42:5451-78; doi: 10.1002/sim.9921
Öner A, Dittrich H, Arslan F, et al. 2023 Comparison of telemonitoring combined with intensive patient support with standard care in patients with chronic cardiovascular disease – a randomized clinical trial. Eur J Med Res 28:22; doi: 10.1186/s40001-023-00991-1
Seiffert M, Vonthein R, Baumgartner H, et al. 2023 Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients at low to intermediate surgical risk: rationale and design of the randomised DEDICATE trial. EuroIntervention 19:652-8; doi: 10.4244/EIJ-D-23-00232
Thalén F, Köhne CG & Bleidorn C 2023 Patchwork: Alignment-Based Retrieval and Concatenation of Phylogenetic Markers from Genomic Data. Genome Biology and Evolution, Volume 15, Issue 12, December 2023, evad227; doi: 10.1093/gbe/evad227
Vila-Farré M, Rozanski A, Ivanković M, et al. 2023 Evolutionary dynamics of whole-body regeneration across planarian flatworms. Nat Ecol Evol 7, 2108–2124; doi: 10.1038/s41559-023-02221-7
Ziegler A, Öner A, Quadflieg G, et al. 2023 Cost-effectiveness of a telemonitoring programme in patients with cardiovascular diseases compared with standard of care. Heart 109:1617-23; doi: 10.1136/heartjnl-2023-322518
2022
Betschart RO, Thiéry A, Aguilera-Garcia D, et al. 2022 Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment. Sci Rep 12:21502; doi: 10.1038/s41598-022-26181-3
Cavus E, Schneider JN, Bei Der Kellen R, et al. 2022 Impact of sex and cardiovascular risk factors on myocardial T1, extracellular volume fraction, and T2 at 3 Tesla: results from the population-based, Hamburg City Health Study. Circ Cardiovasc Imaging 15:e014158; doi: 10.1161/CIRCIMAGING.122.014158
Heßler N & Ziegler A 2022 Evidence-based recommendations for increasing the citation frequency of original articles. Scientometrics 127:3367-81; doi: 10.1007/s11192-022-04378-7
Petersen EL, Goßling A, Adam G, et al. 2022 Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme. Eur Heart J 43:1124-37; doi: 10.1093/eurheartj/ehab914
Schultz J, Freibothe I, Haase M, et al. 2022 Distribution of RET proto-oncogene variants in children with appendicitis. Mol Genet Genomic Med 10:e1864; doi: 10.1002/mgg3.1864
2021
Leonhardt H, Ziegler A, Lauer G & Franke A 2021 Osteosynthesis of the mandibular condyle with magnesium-based biodegradable headless compression screws show good clinical results over a 1-year follow-up period. J Oral Maxillofac Surg 79:637-643; doi: 10.1016/j.joms.2020.02.025
Sonnow L, Ziegler A, Pöhler GH, et al. 2021 Alterations in magnetic resonance imaging characteristics of bioabsorbable magnesium screws over time in humans: a retrospective single center study. Innovative Surgical Sciences 6:105-13; doi: 10.1515/iss-2021-0032.
Sörensen NA, Goßling A, Neumann JT, et al. 2021 Diagnostic Validation of a High-Sensitivity Cardiac Troponin I Assay. Clin Chem 67:1230-9; doi: 10.1093/clinchem/hvab070.
Ziegler A, Forßmann K, Konopka S & Krockenberger K. A modular approach to combine postmarket clinical follow-up studies and postmarket surveillance studies. Methods Inf Med 60:116-22; doi: 10.1055/s-0041-1735165.