CV Prof. Dr. Andreas Ziegler

Research Interests

1. genetic epidemiology, biomarker studies,
2. machine learning,

3. clinical trials with focus on medical devices,

patientreported outcomes.

Work Experience

Since 2020

Scientific director and CEO of Cardio-CARE, Medizincampus Davos


CEO of StatSol: scientific consulting, statistical consulting, scientific writing


Scientific advisor, AMEDON GmbH, Lübeck


Professor and Head, University Medical Center Schleswig-Holstein – Campus Lübeck, University of Lübeck, Institute of Medical Biometry and Statistics


Scientific employee/assistant professor/university researcher and lecturer (“Hochschuldozent”), Philipps-Universität Marburg, Institute of Medical Biometry and Epidemiology


Assistant professor (“Wissenschaftlicher Assistent”), Philipps-University of Marburg, Institute of Medical Sociology


Scientific employee, Bergische Universität – GH Wuppertal, Department of Economics, Institute of Statistics

Education and Training


Extension of venia legendi by Medical Biometry and Epidemiology, Faculty of Human Medicine, Philipps-Universität Marburg


Habilitation for Genetic Epidemiology, Faculty of Human Medicine, Philipps- Universität Marburg


Doctoral degree (Dr. rer. nat.) in Statistics, Universität Dortmund


Diploma in Statistics, Ludwig-Maximilians-Universität München

Selected Honors and Awards

Since 2022

Group leader at the Swiss Institute of Bioinformatics (SIB)


Accredited Professional Statistician (PSTAT) of the American Statistical Association

Since 2016

Honorary Professor for Biostatistics at the School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, South Africa


Leadership Award of the International Genetic Epidemiology Society


Susanne-Dahms-Medaille of the German Region of the International Biometric Society for the special merits in Biometry


Jens-Kirsch-Preis of the German Society of Coloproctology, together with T. Schwandner, W. Kierer, R. Scherer, R. Bouchard, and G. Kolbert for the work “Triple Target Treatment (3T) is more effective than biofeedback alone for anal incontinence: The 3T-AI Study”


Elected member of the International Statistical Institute


Fritz-Linder-Forumpreis of the German Association for Surgery, together with G. Fitze, H. Luksch, I. R. König, H. Görgens, U. Stein, W. Walther, M. Gossen, and H. K. Schackert for the work “Association of functional haplotypes of the RET-Protooncogene promotor with Morbus Hirschsprung”


Certificate “Epidemiology” of the German Epidemiological Association


Certificate “Biometry in Medicine” of the German Association of Medical Informatics, Biometry and Epidemiology and the German Region of the International Biometric Society

Selected Activities in Scientific Societies


Member of the Executive Board of the International Biometric Society


President of the International Genetic Epidemiology Society


Chair of the Representative Council of the International Biometric Society


Member of the Presidium of the German Society for Medical Informatics, Biometry and Epidemiology


Speaker of the German full professors for Medical Informatics, Biometry and Epidemiology


President of the German Region of the International Biometric Society

Selected Editorial Activities

Since 2023

Associate editor of Neurology


Book review editor of Biometrical Journal

Since 2012

Member of the editorial board of Human Genetics


Member of the editorial board of Trials


Member of the editorial board of Deutsche Medizinische Wochenschrift

Since 2007

Associate editor of Statistics in Medicine

Since 2006

Member of the editorial board of Methods of Information in Medicine

Since 1998

Associate editor of the Biometrical Journal



Computing device for estimating the probability of myocardial infarction (Application number WO2022043229A1), Co-Inventor


Use of SNPs of MCH-R for identifying genetic disorders in maintaining the normal body weight. Patent number WO 03/020965 A2, Co-Inventor

Selected Publications

Göpel, W., Kribs, A., Ziegler, A., Laux, R., Hoehn, T., Wieg, C., Siegel, J., Avenarius, S., von der Wense, A., Vochem, M., Groneck, P., Weller, U., Möller, J., Härtel, C., Haller, S., Roth, B. & Herting, E., on behalf of the German Neonatal Network (2011): Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial. The Lancet, 378, 1627-1634. doi:10.1016/S0140-6736(11)60986-0

Samani N.J., Erdmann J., Hall A.S., Hengstenberg C., Mangino M., Mayer B., Dixon R.J., Meitinger T., Braund P., Wichmann H.E., Barrett J.H., König I.R., Stevens S., Szymczak S., Tregouet D.A., Iles M.M., Pahlke F., Pollard H., Lieb W., Cambien F., Fischer M., Ouwehand W., Balmforth A.J., Baessler A., Ball S.G., Strom T.M., Brænne I., Gieger C., Deloukas P., Tobin M.D., Ziegler A., Thompson J.R. & Schunkert H., Wellcome Trust Case Control Consortium, Cardiogenics Consortium (2007): Genomewide association analysis of coronary artery disease. The New England Journal of Medicine, 357, 443453. doi:10.1056/NEJMoa072366

Wright, M. N. & Ziegler, A. (2017): ranger: a fast implementation of random forests for high dimensional data in C++ and R. Journal of Statistical Software, 77:1.

Ziegler, A. (2011): Generalized estimating equations. Lecture Notes in Statistics. New York:
Springer. ISBN: 9781461404989

Ziegler A., König I.R. (2010): A Statistical Approach to Genetic Epidemiology: Concepts and Applications. With an ELearning Course by Friedrich Pahlke. 2nd ed. Weinheim: Wiley
VCH. ISBN: 9783527323890

General information about publications: 

8 books, more than 500 articles in peerreviewed journals. Total IF > 2500